The Australian Proteome Analysis Facility (APAF), hosted at Macquarie University, has been providing state-of-the-art proteomics and mass spectrometry services for Australian and international researchers since it’s foundation over 25 years ago. APAF is supported by NCRIS through BioPlatforms Australia and is proudly NATA-accredited for proteomics analyses to the ISO 17025 standard. We have strong track records in delivering high quality results for our research and industry partners, and collaborators.
APAF houses a wide range of mass spectrometers to cater for a wide variety of different MS-based proteomics experiments. Our team of highly experienced scientists are ready to support your research at every step of the process, from advice on experimental design, performing sample preparation and data acquisition, through to reporting, statistical and bioinformatic analysis. We support many MS-based proteomic techniques including, but not limited to, protein identification from intact proteins and/or digests, quantitative proteomics (label-free DIA and DDA, or labelled experiments), protein-protein interaction analysis (by crosslinking MS, co-immunoprecipitations/pulldowns, and other methods), post-translational modification analysis (including phosphorylation, methylation, redox and glycan analysis), and targeted MS assays. Our team has extensive experience in handling difficult samples, and analysis of non-model organisms. APAF is also well equipped to analyse proteins using non-MS based techniques through amino acid analysis, or emerging techniques (e.g., mass photometry, and computational modelling).
Here, we highlight our expanding capability for protein analysis, including cutting edge instrumentation and advances in method development, and highlight successes in collaboration with researchers and industry, both nationally and internationally.